โรคปอดบวม/ ปอดอักเสบ (Pneumonia)

PneumoniaSteele CMarrero LSwain SHarmsen AGZheng MBrown GDGordon SShellito JEKolls JK., “Alveolar macrophage-mediated killing of Pneumocystis carinii f. sp. muris involves molecular recognition by the Dectin-1 beta-glucan receptor.” Department of Pediatrics, Division of Pulmonology, Children’s Hospital of Pittsburgh, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA. J Exp Med. 198(11): 1677-88; Dec 2003.: Quote: “…these results show that nonopsonic phagocytosis and subsequent killing of P. carinii [a frequent cause of pneumonia in immunocompromised individuals] by alveolar macrophages is dependent upon recognition by the Dectin-1 beta-glucan receptor [activated by beta-glucan ingestion in the Dectin-1 beta-glucan receptor].”

Pneumonia: Maurici da Rocha e Silva et al; “Infection Prevention in Patients with Severe Multiple Trauma with the Immunomodulater Beta 1-3 Polyglucose (glucan);” Surgery, Gynecology & Obstetrics; 177:383-388. 1993.  Quote:  “The incidence of hospital pneumonia of 55% and sepsis of 35% confirms results of previous studies of patients with multitrauma. Glucan decreased pneumonia and sepsis to a significantly lower level of 9.5%….The mortality rate related to infection decreased from 30.0 to 4.8%. The lower number of instances of pneumonia and sepsis….decreased the period of time in the intensive care and the hospital, with a global reduction of 40% on hospital cost.”


 

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